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Resource constrained small satellites need
2020-08-04

Resource constrained small satellites need to detect more CFEs with less time and memory, so neither the error detection rate nor time and memory overhead involved alone can reflect the effectiveness of the CFC techniques. We employ an evaluation factor to evaluate the entire effectiveness of the CF
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Quinacrine hydrochloride hydrate br Conflict of interest br
2020-08-04

Conflict of interest Acknowledgement Introduction Ligand-gated chloride channels (LGCCs) play a physiologically important role as neurotransmitter receptors that commonly mediate inhibitory signals in the nervous systems of animals [1,2]. These chloride channels, including γ-aminobutyric Qu
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For the current studies we
2020-08-04

For the current studies, we used the selective Epac agonist 8CPT-AM to directly activate the proteins. We chose this pharmacological approach since it allows a direct activation of Epacs rather than using receptor agonists such as PGE2 which could introduce confounding variables. One potential conce
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The expression of EP receptor in the
2020-08-04

The expression of EP4 receptor in the skin has previously been investigated in mice (Lee et al, 2005, Tober et al, 2007). While it is well established that the EP4 receptor can be detected by RT-PCR (Lee et al, 2005, Rundhaug et al, 2011), contradictory findings have been reported regarding the expr
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br Transparency document br Introduction
2020-08-04

Transparency document Introduction Cigarette smoke is modifiable factors to alter the neurovascular functions. Now a day, cigarette smoking in public place is offense due to toxic exposure cause the neurological and respiratory system damage to non-smoker population [1]. A literature survey ex
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Despite the differences in the clustering abilities of
2020-08-04

Despite the differences in the clustering abilities of DDR1b versus DDR2 upon ligand administration, we also noted striking similarities in the spatial distribution and phosphorylation of DDR1b-YFP and DDR2-GFP. We show for the first time that in MC3T3-E1 cells, after 4 h of collagen administration,
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The phytochemical sulforaphane SFN first identified
2020-08-04

The phytochemical sulforaphane (SFN), first identified in broccoli sprouts and present in high concentrations in most cruciferous vegetables (Whiteside et al., 2013), has been shown to modulate multiple targets involved in cancer development (Bayat Mokhtari et al., 2017). SFN activates different sig
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br E intracellular localization br Regulation of E by other
2020-08-04

E1 intracellular localization Regulation of E1 by other post-translational modifications Concluding remarks Acknowledgments We apologize to those whose work was not included because of space considerations or whose papers were unintentionally omitted. We thank Dr Peter Bullock (Tufts Uni
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The tonic immobility TI response is an innate
2020-08-03

The tonic immobility (TI) response is an innate and reversible defensive response characterized by profound physical inactivity and relative lack of responsivity to environmental stimuli (Klemm, 2001, Ratner, 1967). This behavior is shown during situations of extreme, inescapable threat (Gallup, 197
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Continuing with the development of the BCA
2020-08-03

Continuing with the development of the BCA CPA-8, this work aimed to study the potential use of different types of packaging to prolong bacterium viability and preservation. In order to do this, we studied the following: (i) the effect of different materials (bags or flasks), SU11274 conditions, an
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mst1 kinase Given innate differences in PFC DA tone between
2020-08-03

Given innate differences in PFC DA tone between P and Wistar rats (Engleman et al., 2006), coupled with our findings that COMT expression differs by strain and sex in the PFC, we hypothesize that tolcapone exerts its effects primarily on cortical catecholamines. However, high COMT expression in the
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It is important to acknowledge
2020-08-03

It is important to acknowledge a second COMT (COMT2), which is related to COMT1 that regulates dopamine levels in the brain, is widely expressed in inner and outer hair cells of the cochlea. A mutation to a COMT2 shows defects in cochlear function in both mice and humans that are related to hearing
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br Results br Discussion Many studies have
2020-08-03

Results Discussion Many studies have shown that intrinsic properties of the E2 enzyme govern the nature of the Ub modification, including both the multiplicity of the Ub modification and the specific Caspase-3, human recombinant proteinase type in the case of polyubiquitin chains [3], [4], [9
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br Conclusions The s s of Pb and Cu contaminated
2020-08-03

Conclusions The s/s of Pb and Cu contaminated slurry using cement and rice husk ash (RHA) was investigated. This study investigated the potential of replacing 20%–40% of the cement used for the s/s of Cu and Pb with RHA. It was observed that an increase in the binder content from 100 kg/m3 – 300
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The evaluation of ET in children
2020-08-03

The evaluation of ET-743 in children initially lent credence to this theory. In a phase I study of 13 patients, 2 out of 3 Ewing sarcoma patients treated with the drug responded, one patient with widely metastatic disease had a complete response (Lau et al., 2005). In another case series of Ewing sa
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